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apple inc
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Certara L.P
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OriginLab corp
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SoftMax Inc
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HULINKS Inc
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CH Instruments
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AstraZeneca ltd
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Molecular Devices LLC
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AstraZeneca ltd
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MathWorks Inc
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Minitab Inc
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Image Search Results
Journal: Molecular cancer therapeutics
Article Title: Preclinical Evaluation of the Efficacy of a Cyclin-dependent Kinase Inhibitor Ribociclib in Combination with Letrozole Against Patient-Derived Glioblastoma Cells
doi: 10.1158/1535-7163.MCT-25-0277
Figure Lengend Snippet: Brain and Systemic Pharmacokinetics of ribociclib. A) Plasma levels of ribociclib in SD rats (N = 5) at single i.p. dose of 100 mg/kg. (Corrected with protein binding ~28%) and B) Brain extracellular fluid (ECF) concentration–time profile of ribociclib in SD rats after single i.p. (N = 5) dose of 100 mg/kg (corrected with in-vitro recovery 6.1%). Data are presented as mean ± SD. The best-fit regression curves are plotted using Phoenix WinNonLin ® (Certara)
Article Snippet: The best-fit regression curves are plotted using
Techniques: Drug discovery, Clinical Proteomics, Protein Binding, Concentration Assay, In Vitro